Center for Advanced Microscopy and Nikon Imaging Center

The Center for Advanced Microscopy (CAM) at Northwestern offers state-of-the art instrumentation and services for the study of biological processes at the whole animal, tissue, cellular and subcellular levels. The facility's basic services include electron microscopy, super resolution microscopy (SIM & STORM), fluorescent laser scanning and spinning disk microscopy, fluorescent lifetime imaging, fluorescence correlation spectroscopy microscopy, automated high throughput tissue cytometry, laser capture microdissection, mutliphoton imaging, and whole animal bioluminescent and fluorescent imaging. Additionally we provide microinjection equipment, chambers for stable live cell observation, and anesthesia equipment. CAM staff members provide training on numerous different instrument platforms, consultation on experiment design, as well as digital image processing and image analysis. We are a reference site for several companies including TissueGnostics and ISS (developer of the ISS ALBA). CAM is one of three Nikon Imaging Centers in the US, allowing us access and excellent support from Nikon to develop innovative solutions for the cutting edge imaging needs of users. This relationship has allowed our users to push super-resolution technologies to permit multi-color, 3D and live-cell applications. Additionally, we have been working together with Nikon to add confocal laser scanning to a low magnification upright dissection microscope, which is particularly useful to researchers interested in visualizing thick samples (such as epidermal raft cultures) at increased cellular resolution. We are also currently expanding our full service electron microscopy offerings. Recently, we obtained a Leica Freeze Substitution Unit for TEM sample preparation allowing for improved sample quality and streamlined work-flow.

Please feel free to contact us with questions.

For the Research Newsletter featuring CAM, please click here.

Visit Facility Website

Campus: 

Chicago

Location: 

303 E. Chicago Ave. Morton Bldg, 2nd floor
Chicago , IL 60611
United States
Phone: 312-503-2841

Equipment / Supplies Available at this Facility

Equipment / Supplies Available at this Facility: 

Services

FRET
FRAP
Volocity
Microinjection
Needle Puller
Electron microscopy of tissue and cultured cell specimens
Full Service Sample Preparation and Sampling
Critical Point Drying
Immunogold EM
Platinum-replica electron microscopy
CLEM Correlative Light and Electron Microscopy
Sputter-coating
Digital and conventional EM Image Acquisition
Fluroescence-based Non-invasive small animal imaging
Fluroescence-based Non-invasive small animal intravital imaging
Individual training on each instrument
Bioluminescence
TIRF Total Internal Reflection Fluorescence
IVIS Spectrum in-vivo bioluminescence / fluorescence imager
Poster Printing