Animal Preclinical Services

CAMI staff

The Center for Advanced Molecular Imaging (CAMI) provides access to imaging modalities ranging from the nanometer scale to whole animal imaging. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture.  Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis.  Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.

CAMI also houses a 2 photon confocal microscope operated by QBIC and atomic force microscopes operated by NIFTI.

The Microsurgery Core is dedicated to assisting investigators with a central resource for creating mouse and rat models of tissue and organ transplantation. It provides a valuable and unique research opportunity for translational research from animal studies to human diseases. For more information on this facility, please click here.

 

The Behavioral Phenotyping Core (BPC) helps investigators examine their mice and rats for changes in behavior. BPC's mission is to make available to funded research projects a facility to determine the behavioral effects of genetic manipulations, potential pharmaceuticals, aging, and other manipulations upon normal behavior, and the learning and memory capacities of rodents used as model systems. We can also work with PIs needing to gather pilot data. For more information about this facility, click here.

Individuals wishing to use the BPC are encouraged to contact Dr. Craig Weiss during the design stage of the project. 

The selection of animal strain, age and gender should be considered carefully.  Contact Dr. Weiss to discuss  selections.  For a discussion of gender differences affecting research with humans see: http://www.womenshealth.northwestern.edu/research

The BPC has multiple assays in the same room and even multiple assays in the same chamber.  This arrangement maximizes flexibility and efficiency within our limited space, but it precludes the use of an on-line reservation calendar. Scheduling is done by emailing either Dr. Weiss (cweiss@northwestern.edu) or Mary Kando (Mary.Kando@northwestern.edu).