Training

The Clean Catalysis (CleanCat) Core at Northwestern University is dedicated to aiding investigators in the advancement of understanding the catalytic function of materials for environmental and energy processes. We provide students with the necessary tools for testing the catalytic properties of materials and obtaining insight into reaction mechanisms occurring on surfaces. Not only do we provide the neccessary equipment for these studies, but also the guidance of an experienced lab manager who takes a hands-on-approach to educating students about experimental design and proper technique so they become experts themselves. We don't merely train students to use equipment, we teach students how to collect data that answers their research questions.

For more information about this facility, click here. 

 

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The recognition of the complexity of flow cytometric analysis has caused many journals and granting organizations to scrutinize flow data. Thus the core flow lab is becoming an important research resource as well as service provider and a prudent investment for academic institutions. The challenge for the academic core facility is to meet both the scientific and technical mission by providing high quality services in a cost-effective and timely manner. Serving 175+ investigators on the Chicago and Evanston Campuses, with 3 sorters and 6 benchtop analyzers with 16+ color capabilities, we have developed a paradigm to balance productivity with quality to minimize the cost per research project, keep overall costs contained, and provide the necessary scientific support. Central to this paradigm is a close working relationship with investigators to define their projects in the early stages of development to make optimal and efficient use of flow cytometry..For more information about this facility, click here.

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The Research Shop

Located in the Technological Institute, the Research Shop consists of three elements for providing services to the Research community:

  • The Design & Engineering Shop has a professional engineering and fabrication staff providing design and engineering services that include brainstorming, design and engineering consultation along with CAD and CAM consulting (no fee), design engineering, including integration of electronics, services (fee-basis) and fabrication specification drawing development (fee-basis).
  • The Professional Shop is a machine shop staffed by professional machinists for fabricating components and assemblies of instruments (fee-based). Besides traditional machining tools, there is access to laser & waterjet cutting and 3D printing in plastics and metal (tba).
  • The Student Shop is a maker and consulting space where student users can fabricate and build their own projects. Professional engineering and fabrication consulting is available during business hours (no fee). Access is available 24 hours a day, 7 days a week provided safety requirements are met. Trained safety monitors are provided during some of these hours; accompaniment by a trained buddy is required during others. Classes in machine shop tools usage and shop safety are offered for no-cost (beginning June 1st, 2017).

To make a service request, log in to NUcore.

For more information about this facility, click here.

For the Research Newsletter featuring the Instrument Shop, click here.

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The Central Laboratory for Materials Mechanical Properties (CLaMMP) contains testing machines and accessories for conducting educational, research, and outreach experiments on most solid materials. The lab is available for use for both the Northwestern community and non-Northwestern researchers on an hourly-fee basis. The facility provides testing equipment for studying the mechanical behavior of materials. For more information about this facility, click here.

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Atom Probe Tomography (APT) produces a three-dimensional (3D) atom-by-atom image of a sample, with sub-nanometer spatial resolution and a typically 150 x 150 x 500 nm^3 analyzed volume, by simultaneous high resolution imaging and time of flight mass spectrometry. APT is particularly suited to study nano or nanostructured materials. The same samples can also be characterized by Transmission Electron Microscopy (TEM), in a correlative study. To compare these experimental results with atomistic simulations on the same size scale, ab-initio calculations and Monte-Carlo simulations can be performed at our facility. NUCAPT operates a CAMECA LEAP 4000 XSi tomograph. Specimen tips can be prepared by electropolishing (metals) and from almost any material by FIB ( Focused-ion beam milling ). Ion beam sputter deposition creates thin film structures that aid with APT specimen preparation. Vacuum arc melting systems are available for syntesizing alloys and compounds. Thermocalc and MEDEA software packages are available for thermodynamic calculations and materials simulations.  For more information about this facility, click here.

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The Biological Imaging Facility (BIF) is a shared-use research and training resource available to all NU researchers. BIF is organized so users can prepare samples, capture and analyze images, and create final presentations in one facility. Training for all instruments is available on a regular basis so users can acquire data quickly and efficiently. We are continuously looking for new ways to enhance existing equipment, acquire new tools, and keep pace with current techniques. For more information about this facility, click here.

For the Research Newsletter article featuring BIF, click here

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The  Pathology Core Facility (PCF) of Robert H. Lurie Comprehensive Cancer Center (RHLCCC) at Northwestern University is established in 1997.  PCF is functionally divided into three divisions/units, including core lab, biorepository and clinical trials unit.  Core lab includes all related tasks of routine histology, immunohistochemistry, molecular work, and digital pathology (all aspects of a research-based anatomic pathology laboratory including formalin fixation and paraffin embedding, automated and manual immunohistochemistry, tissue microarray design and construction, and automated whole slide scanning for digital pathology applications, including advanced image analysis capabilities). Biorepository division includes tissue and biospecimen procurement (a workflow that complements clinical patient care, the consent procedures which include statement of basic, translational and clinical research and PDX studies for potential therapies), detailed sample annotation (pre-analytic variables such as cold post-surgery time, frozen section evaluation, specimen tracking, and a quality management program); and well-controlled biospecimens and procedures (ensuring that clinically meaningful and reproducible data emerge from investigation). The clinical trials unit (CTU) provides service of institution, regional and national network and prepares trial cases of fast turnaround time and high quality trial materials and patients’ satisfaction. In conjunction with the Cancer Center’s Clinical Trials Office, the clinical trials unit participates in both industry based clinical trials and investigator initiated clinical trials. 

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The Quantitative Bio-element Imaging Center (QBIC) provides researchers with access to state-of-the-art imaging and quantification instrumentation while supporting its use with an expert technical staff that offers a range of services, including instrument training, sample preparation and analysis, experiment design, and grant proposal assistance.  The combination of both extremely high sensitivity elemental analysis and high resolution imaging enables QBIC customers to perform cutting edge experiments with ample staff support. For more information about this facility, click here. 

 

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The Center for Advanced Microscopy (CAM) at Northwestern offers state-of-the art instrumentation and services for the study of biological processes at the whole animal, tissue, cellular and subcellular levels. The facility's basic services include electron microscopy, super resolution microscopy (SIM & STORM), fluorescent laser scanning and spinning disk microscopy, fluorescent lifetime imaging, fluorescence correlation spectroscopy microscopy, automated high throughput tissue cytometry, laser capture microdissection, mutliphoton imaging, and whole animal bioluminescent and fluorescent imaging. Additionally we provide microinjection equipment, chambers for stable live cell observation, and anesthesia equipment. CAM staff members provide training on numerous different instrument platforms, consultation on experiment design, as well as digital image processing and image analysis. We are a reference site for several companies including TissueGnostics and ISS (developer of the ISS ALBA). CAM is one of three Nikon Imaging Centers in the US, allowing us access and excellent support from Nikon to develop innovative solutions for the cutting edge imaging needs of users. This relationship has allowed our users to push super-resolution technologies to permit multi-color, 3D and live-cell applications. Additionally, we have been working together with Nikon to add confocal laser scanning to a low magnification upright dissection microscope, which is particularly useful to researchers interested in visualizing thick samples (such as epidermal raft cultures) at increased cellular resolution. We are also currently expanding our full service electron microscopy offerings. Recently, we obtained a Leica Freeze Substitution Unit for TEM sample preparation allowing for improved sample quality and streamlined work-flow.

Please feel free to contact us with questions.

For the Research Newsletter featuring CAM, please click here.

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